Hesperis Course - Scientific Programme Frame


Below the scientific programme frame of the Hesperis Course is presented. Each Hesperis Course is based on this scientific frame.

2 days Transplantation Immunology
- Allorecognition
-
Immunobiology of acute and chronic rejection

Tolerance in transplantation
-
Immunological basis
-
Experimental Tolerance
-
Clinical approaches

HLA-system

- Immunogenetics and histocompatibility

Cellular and molecular biology techniques in transplantation


1 dayClinical definition of rejection
- Hyperacute and delayed hyperacute
- Acute
- Chronic

Histopathology of transplanted organs
- Kidney
- Liver
- Heart – Lung
- Pancreas

- Reciprocal patterns

1,5 days
Immunosuppression
- Non-specific
  a.
Biological Agents
      - Monoclonal antibodies
      -
Polyclonal antibodies
      -
Fusion proteins
  b.
Chemical Agents
      
- Corticosteroids
      -
Anti-purine/pyrimidine
      -
Anti-calcineurins
      -
mTor inhibitors
      -
Others
  c. Protocol rules
      -
Side effects
      -
Toxicities
      -
Cancers
      -
Infections: fungal, bacterial, viral hepatotrophic/non-hepatotrophic
- Specific (Immunosuppression aiming at inducing tolerance)

Monitoring of the transplant recipient
- Clinical monitoring

- Immunological Monitoring

1 dayOrgan procurement and organ preservation
- Procurement of cadaver organs
- Organs from marginal cadavers
- Living-related and unrelated donation

- Organ preservation
      -
Above 0°C

      - Below 0°C
- Ischemia/reperfusion related complications


Ethics of organ transplantation and procurement

 0,5 day

Organ specific aspects related to transplantation
Abdominal organs: r
enal transplantation
-
Surgical techniques (ex- and implantation)
-
Indications
-
Specific Complications
-
Results
-
Paediatric specificities

0,5 dayOrgan specific aspects related to transplantation
Abdominal organs: liver
transplantation
-
Surgical techniques (ex- and implantation)
-
Indications
-
Specific Complications

- Results
- Paediatric specificities


0,5 dayOrgan specific aspects related to transplantation - abdominal organs

Pancreas transplantation

- Surgical techniques (ex- and implantation)
-
Indications
-
Specific Complications
-
Results
-
Paediatric specificities

Islets

Small Bowel transplantation
-
Surgical techniques (ex- and implantation)
-
Indications
-
Specific Complications
-
Results
-
Paediatric specificities

0,5 dayOrgan specific aspects related to transplantation - thoracic organs 

Heart, Heart-Lung transplantation
- Surgical techniques (ex- and implantation)
- Indications
- Specific Complications
- Results
- Paediatric specificities

Lung transplantation
-
Surgical techniques (ex- and implantation)
-
Indications
-
Specific Complications
-
Results
-
Paediatric specificities

0,5 dayCell and tissue transplantation
- Composite tissues
- Bone Marrow and Stem Cell transplantation
- Neural Tissue
- Regenerative Medicine
- Tissue engineering
- Cornea transplantation

1 day

New hot topic

History of Transplantation

Xenotransplantation

Statistics & Clinical research design